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COX2 genetic variation, NSAIDs, and advanced prostate cancer risk

Collective evidence suggests that cyclooxygenase 2 (COX2) plays a role in prostate cancer risk. Cyclooxygenase 2 is the major enzyme that converts arachidonic acid to prostaglandins, which are potent mediators of inflammation. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the enzymatic activ...

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Detalhes bibliográficos
Main Authors: Cheng, I, Liu, X, Plummer, S J, Krumroy, L M, Casey, G, Witte, J S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360347/
https://ncbi.nlm.nih.gov/pubmed/17609663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603874
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