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p53 and its isoforms in cancer
p53, p63 and p73 are members of the p53 gene family involved in development, differentiation and response to cellular stress. p53 gene is a transcription factor essential for the prevention of cancer formation. The p53 pathway is ubiquitously lost in human cancer either by p53 gene mutation (60% of...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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Nature Publishing Group
2007
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360320/ https://ncbi.nlm.nih.gov/pubmed/17637683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603886 |
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