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Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients

Transforming growth factor-β1 (TGF-β1), a tumour suppressing as well as tumour-promoting cytokine, is stored as an extracellular matrix-bound latent complex. We examined TGF-β1 activation and localisation of TGF-β1 activity in gastric cancer. Gastric tumours showed increased stromal and epithelial t...

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Detalhes bibliográficos
Main Authors: Hawinkels, L J A C, Verspaget, H W, van Duijn, W, van der Zon, J M, Zuidwijk, K, Kubben, F J G M, Verheijen, J H, Hommes, D W, Lamers, C B H W, Sier, C F M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360315/
https://ncbi.nlm.nih.gov/pubmed/17637685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603877
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