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Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?

Gemcitabine is a deoxycytidine analogue that has a broad spectrum of antitumour activity in many solid tumours including pancreatic cancer. We have recently carried out a pharmacogenomic study in cancer patients treated with gemcitabine, and found that one genetic polymorphism of an enzyme involved...

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Detalhes bibliográficos
Main Authors: Ueno, H, Kiyosawa, K, Kaniwa, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360307/
https://ncbi.nlm.nih.gov/pubmed/17595663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603860
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