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DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers

The BRCA1 gene product helps to maintain genomic integrity through its participation in the cellular response to DNA damage: specifically, the repair of double-stranded DNA breaks. An impaired cellular response to DNA damage is a plausible mechanism whereby BRCA1 mutation carriers are at increased r...

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Detalhes bibliográficos
Main Authors: Kotsopoulos, J, Chen, Z, Vallis, K A, Poll, A, Ainsworth, P, Narod, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360222/
https://ncbi.nlm.nih.gov/pubmed/17213827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603528
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