A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer

Gemcitabine (GEM)-based chemotherapy is regarded as the standard treatment of pancreatic adenocarcinoma, but yields a very limited disease control. Very few studies have investigated salvage chemotherapy after failure of GEM or GEM-containing chemotherapy and preclinical studies attempting to widen...

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Detalhes bibliográficos
Main Authors: Mercalli, A, Sordi, V, Formicola, R, Dandrea, M, Beghelli, S, Scarpa, A, Di Carlo, V, Reni, M, Piemonti, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360188/
https://ncbi.nlm.nih.gov/pubmed/17426706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603726
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