A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer

We sought to evaluate the efficacy and safety data of a combination regimen using weekly irinotecan in combination with capecitabine and concurrent radiotherapy (CapIri-RT) as neoadjuvant treatment in rectal cancer in a phase-II trial. Patients with rectal cancer clinical stages T3/4 Nx or N+ were r...

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Main Authors: Willeke, F, Horisberger, K, Kraus-Tiefenbacher, U, Wenz, F, Leitner, A, Hochhaus, A, Grobholz, R, Willer, A, Kähler, G, Post, S, Hofheinz, R-D
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360100/
https://ncbi.nlm.nih.gov/pubmed/17325705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603645
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