A phase I/II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study

The objective of this study was to evaluate the maximum tolerated dose (MTD) and recommended dose of irinotecan administered as a 5-day schedule synchronously with 5-fluorouracil (5FU), leucovorin (LV) and preoperative pelvic radiation (45 Gy) for primary borderline/unresectable, locally advanced re...

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Hlavní autoři: Glynne-Jones, R, Falk, S, Maughan, T S, Meadows, H M, Sebag-Montefiore, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360056/
https://ncbi.nlm.nih.gov/pubmed/17262086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603570
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