Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation

Pancreatic ductal adenocarcinoma (PDAC) is characterised pathologically by a marked desmoplastic stromal reaction that significantly reduces the sensitivity and specificity of cytogenetic analysis. To identify genetic alterations that reflect the characteristics of the tumour in vivo, we screened a...

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Bibliographic Details
Main Authors: Harada, T, Baril, P, Gangeswaran, R, Kelly, G, Chelala, C, Bhakta, V, Caulee, K, Mahon, P C, Lemoine, N R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359995/
https://ncbi.nlm.nih.gov/pubmed/17242705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603563
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