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WTH3 is a direct target of the p53 protein

Previous results showed that overexpression of the WTH3 gene in multidrug resistance (MDR) cells reduced MDR1 gene expression and converted their resistance to sensitivity to various anticancer drugs. The WTH3 gene promoter was found to be differentially regulated in paired MDR vs non-MDR MCF7 cells...

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Bibliographic Details
Main Authors: Tian, K, Wang, Y, Xu, H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359938/
https://ncbi.nlm.nih.gov/pubmed/17426708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603724
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