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Anticancer prodrugs of butyric acid and formaldehyde protect against doxorubicin-induced cardiotoxicity
Formaldehyde has been previously shown to play a dominant role in promoting synergy between doxorubicin (Dox) and formaldehyde-releasing butyric acid (BA) prodrugs in killing cancer cells. In this work, we report that these prodrugs also protect neonatal rat cardiomyocytes and adult mice against tox...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359917/ https://ncbi.nlm.nih.gov/pubmed/17473824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603781 |
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