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Mathematical models of the VEGF receptor and its role in cancer therapy

We present an analysis of a stochastic model of the vascular endothelial growth factor (VEGF) receptor. This analysis addresses the contribution of ligand-binding-induced oligomerization, activation of src-homology 2 domain-carrying kinases and receptor internalization in the overall behaviour of th...

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Autors principals: Alarcón, Tomás, Page, Karen M
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359839/
https://ncbi.nlm.nih.gov/pubmed/17251148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0170
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