Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen

The distribution of carcinoembryonic antigen (CEA) in colorectal cancer (CRC) differs from that in normal colorectal tissue, being found on all borders of the cell membrane and hence enabling access to intravenous antibody, making CEA a good target for antibody-based therapy. The distinctive anti-CE...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Conaghan, P J, Ashraf, S Q, Tytherleigh, M G, Wilding, J L, Tchilian, E, Bicknell, D, Mortensen, N JMcC, Bodmer, W F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Translational Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359646/
https://ncbi.nlm.nih.gov/pubmed/18349843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604289
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