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Vaccination and the dynamics of immune evasion
Vaccines exert strong selective pressures on pathogens, favouring the spread of antigenic variants. We propose a simple mathematical model to investigate the dynamics of a novel pathogenic strain that emerges in a population where a previous strain is maintained at low endemic level by a vaccine. We...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2358969/ https://ncbi.nlm.nih.gov/pubmed/17210532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2006.0167 |
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