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An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains

The host response to Gram-negative bacterial infection is influenced by two homologous lipopolysaccharide (LPS)-interactive proteins, LPS-binding protein (LBP) and the bacteridical/permeability-increasing protein (BPI). Both proteins bind LPS via their N-terminal domains but produce profoundly diffe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Iovine, Nicole M., Elsbach, Peter, Weiss, Jerrold
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10973
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