Decreased blood pressure response in mice deficient of the α(1b)-adrenergic receptor

To investigate the functional role of different α(1)-adrenergic receptor (α(1)-AR) subtypes in vivo, we have applied a gene targeting approach to create a mouse model lacking the α(1b)-AR (α(1b)−/−). Reverse transcription–PCR and ligand binding studies were combined to elucidate the expression of th...

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Detalhes bibliográficos
Main Authors: Cavalli, Antonella, Lattion, Anne-Laure, Hummler, Edith, Nenniger, Monique, Pedrazzini, Thierry, Aubert, Jean-François, Michel, Martin C., Yang, Ming, Lembo, Giuseppe, Vecchione, Carmine, Mostardini, Marina, Schmidt, Andrea, Beermann, Friedrich, Cotecchia, Susanna
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23548/
https://ncbi.nlm.nih.gov/pubmed/9326654
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