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Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium

The factors that regulate the perpetuation and invasiveness of rheumatoid synovitis have been the subject of considerable inquiry, and the possibility that nonimmunologic defects can contribute to the disease has not been rigorously addressed. Using a mismatch detection system, we report that synovi...

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Autors principals: Firestein, Gary S., Echeverri, Fernando, Yeo, Michele, Zvaifler, Nathan J., Green, Douglas R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23522/
https://ncbi.nlm.nih.gov/pubmed/9380731
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