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Propofol enhances both tonic and phasic inhibitory currents in second-order neurons of the solitary tract nucleus (NTS)

The anesthetic propofol is thought to induce rapid hypnotic sedation by facilitating a GABAergic tonic current in forebrain neurons. The depression of cardiovascular and respiratory regulation often observed during propofol suggests potential additional actions within the brainstem. Here we determin...

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Bibliographic Details
Main Authors: McDougall, Stuart J., Bailey, Timothy W., Mendelowitz, David, Andresen, Michael C.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2351956/
https://ncbi.nlm.nih.gov/pubmed/18082229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.11.001
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