Prazosin Effects on Objective Sleep Measures and Clinical Symptoms in Civilian Trauma PTSD: A Placebo-Controlled Study

BACKGROUND: Prazosin, a CNS active alpha-1 adrenoreceptor antagonist, has reduced nightmares and sleep disturbance in placebo controlled studies of combat-related PTSD. We evaluated objective sleep parameters and PTSD symptoms in a placebo-controlled prazosin trial for civilian trauma-related PTSD....

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Bibliographic Details
Main Authors: Taylor, Fletcher B., Martin, Patti, Thompson, Charles, Williams, Judi, Mellman, Thomas A., Gross, Christopher, Peskind, Elaine R., Raskind, Murray A.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350188/
https://ncbi.nlm.nih.gov/pubmed/17868655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.07.001
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