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The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses

The c-Jun N-terminal kinase (JNK) pathway can play paradoxical roles as either a pro-survival or a pro-cell death pathway depending on type of stress and cell type. The goal of the present study was to determine the role of JNK pathway signaling for regulating B-cell apoptosis in two important but c...

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Detalhes bibliográficos
Main Authors: Muscarella, Donna E., Bloom, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2349100/
https://ncbi.nlm.nih.gov/pubmed/18201741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.11.032
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