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Insulin and insulin-like growth factor-I acutely inhibit surface translocation of growth hormone receptors in osteoblasts: A novel mechanism of growth hormone receptor regulation

We previously have demonstrated that insulin and insulin-like growth factor-I (IGF-I) down-regulate growth hormone (GH) binding in osteoblasts by reducing the number of surface GH receptors (GHRs). The present study was undertaken to investigate the mechanism of GHR down-regulation. Treatment with 5...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Leung, Kin-Chuen, Waters, Michael J., Markus, Irit, Baumbach, William R., Ho, Ken K. Y.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11381
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