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Dimerization of the Human Papillomavirus Type 16 E2 N Terminus Results in DNA Looping within the Upstream Regulatory Region

Papillomavirus E2 proteins play a central role in regulating viral gene expression and replication. DNA-binding activity is associated with the C-terminal domain of E2, which forms a stable dimer, while the N-terminal domain is responsible for E2's replication and transactivation functions. The...

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Detalhes bibliográficos
Main Authors: Hernandez-Ramon, Elena E., Burns, Julie E., Zhang, Wenke, Walker, Hannah F., Allen, Stephanie, Antson, Alfred A., Maitland, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346762/
https://ncbi.nlm.nih.gov/pubmed/18337573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02388-07
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