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Uniocular Anterior Chamber Inoculation of a Tumor Necrosis Factor Alpha-Expressing Recombinant of Herpes Simplex Virus Type 1 Results in More Rapid Destruction and Increased Viral Replication in the Retina of the Uninoculated Eye

Tumor necrosis factor alpha (TNF-α) has been shown to have a protective role in the eyes and brains of herpes simplex virus type 1 (HSV-1)-infected mice. To determine whether overexpression of TNF-α affected the course of virus infection following uniocular anterior chamber inoculation, a recombinan...

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Detalhes bibliográficos
Main Authors: Fields, Mark A., Zheng, Mei, Wall, Pam, Oberg, Scott, Atherton, Sally S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346751/
https://ncbi.nlm.nih.gov/pubmed/18321975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00082-08
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