The C-Terminal Segment of the Cysteine-Rich Interdomain of Plasmodium falciparum Erythrocyte Membrane Protein 1 Determines CD36 Binding and Elicits Antibodies That Inhibit Adhesion of Parasite-Infected Erythrocytes

Attachment of erythrocytes infected by Plasmodium falciparum to receptors of the microvasculature is a major contributor to the pathology and morbidity associated with malaria. Adhesion is mediated by the P. falciparum erythrocyte membrane protein 1 (PfEMP-1), which is expressed at the surface of in...

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Detalhes bibliográficos
Main Authors: Mo, Min, Lee, Hooi Chen, Kotaka, Masayo, Niang, Makhtar, Gao, Xiaohong, Iyer, Jayasree Kaveri, Lescar, Julien, Preiser, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346709/
https://ncbi.nlm.nih.gov/pubmed/18299339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00480-07
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