Mouse Beta-Defensin-14, an Antimicrobial Ortholog of Human Beta-Defensin-3

Searching the database for mouse homologs of the antimicrobial peptide human beta-defensin-3 (hBD-3) revealed highest identity (69%) to mouse beta-defensin-14 (mBD-14). Recombinant mBD-14 exhibited broad-spectrum, nanomolar microbicidal activity. Treatment of keratinocytes with gamma interferon or t...

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Détails bibliographiques
Auteurs principaux: Hinrichsen, Kerstin, Podschun, Rainer, Schubert, Sabine, Schröder, Jens M., Harder, Jürgen, Proksch, Ehrhardt
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
Sujets:
Susceptibility
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346663/
https://ncbi.nlm.nih.gov/pubmed/18332171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01308-07
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