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In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens

Rx-01_423 and Rx-01_667 are two members of the family of oxazolidinones that were designed using a combination of computational and medicinal chemistry and conventional biological techniques. The compounds have a two- to eightfold-improved potency over linezolid against serious gram-positive pathoge...

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Detalhes bibliográficos
Main Authors: Lawrence, Laura, Danese, Paul, DeVito, Joe, Franceschi, Francois, Sutcliffe, Joyce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346622/
https://ncbi.nlm.nih.gov/pubmed/18316525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01383-07
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