Mitochondrial DNA Content, an Inaccurate Biomarker of Mitochondrial Alteration in Human Immunodeficiency Virus-Related Lipodystrophy

Lipoatrophy is a prevalent side effect of antiretroviral treatment of human immunodeficiency virus (HIV) infection. Its mechanisms are still disputed but include mitochondrial toxicity and, in particular, mitochondrial DNA (mtDNA) depletion induced by nucleoside reverse transcriptase inhibitors. To...

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Autori principali: Kim, Min Ji, Jardel, Claude, Barthélémy, Cyrille, Jan, Véronique, Bastard, Jean Philippe, Fillaut-Chapin, Sandrine, Houry, Sydney, Capeau, Jacqueline, Lombès, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346614/
https://ncbi.nlm.nih.gov/pubmed/18332166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01449-07
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