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Efficacy of Benzoxazinorifamycins in a Mouse Model of Chlamydia pneumoniae Lung Infection

The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight.

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Detalhes bibliográficos
Main Authors: Campbell, Lee Ann, Kuo, Cho-Chou, Suchland, Robert J., Rothstein, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346613/
https://ncbi.nlm.nih.gov/pubmed/18332169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01567-07
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