Human granulocyte colony stimulating factor (hG-CSF): cloning, overexpression, purification and characterization

BACKGROUND: Biopharmaceutical drugs are mainly recombinant proteins produced by biotechnological tools. The patents of many biopharmaceuticals have expired, and biosimilars are thus currently being developed. Human granulocyte colony stimulating factor (hG-CSF) is a hematopoietic cytokine that acts...

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Bibliographic Details
Main Authors: Vanz, Ana LS, Renard, Gaby, Palma, Mario S, Chies, Jocelei M, Dalmora, Sérgio L, Basso, Luiz A, Santos, Diógenes S
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346455/
https://ncbi.nlm.nih.gov/pubmed/18394164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-7-13
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