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The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities

A thiol-acrylate photopolymerization was used to incorporate enzymatically cleavable peptide sequences into PEG hydrogels to induce chondrogenic differentiation of encapsulated human mesenchymal stem cells (hMSCs). An adhesive sequence, RGD, was designed with an MMP-13 specific cleavable linker. RGD...

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Detalhes bibliográficos
Main Authors: Salinas, Chelsea N., Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346439/
https://ncbi.nlm.nih.gov/pubmed/18295878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.01.035
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