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Effect of Phenobarbital on Hepatic Cell Proliferation and Apoptosis in Mice Deficient in the p50 Subunit of NF-κB

Phenobarbital (PB) is a nongenotoxic tumor promoter in the liver. One mechanism by which PB may exert its tumor promoting activity is by inducing oxidative stress. We previously found that PB administration increased hepatic NF-κB DNA binding activity. In this study we examined the hypothesis that t...

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Detalhes bibliográficos
Main Authors: Tharappel, Job C., Spear, Brett T., Glauert, Howard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2344135/
https://ncbi.nlm.nih.gov/pubmed/17963809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.09.019
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