Insulin-like growth factor-1 prevents age-related decrease in specific force and intracellular Ca(2+) in single intact muscle fibres from transgenic mice

In the present work we test the hypothesis that sustained transgenic overexpression of insulin-like growth factor-1 (IGF-1) in skeletal muscle prevents age-related decreases in myoplasmic Ca(2+) concentration and consequently in specific force in single intact fibres from the flexor digitorum brevis...

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Bibliographic Details
Main Authors: González, Estela, Messi, María Laura, Zheng, Zhenlin, Delbono, Osvaldo
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343464/
https://ncbi.nlm.nih.gov/pubmed/12937290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.048165
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