Transgenesis and neuroendocrine physiology: a transgenic rat model expressing growth hormone in vasopressin neurones

Human growth hormone (hGH) and bovine neurophysin (bNP) DNA reporter fragments were inserted into the rat vasopressin (VP) and oxytocin (OT) genes in a 44 kb cosmid construct used to generate two lines of transgenic rats, termed JP17 and JP59. Both lines showed specific hGH expression in magnocellul...

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Bibliografiske detaljer
Main Authors: Wells, Sara E, Flavell, David M, Bisset, Gordon W, Houston, Pamela A, Christian, Helen, Fairhall, Keith M, Robinson, Iain C A F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343152/
https://ncbi.nlm.nih.gov/pubmed/12813157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.037655
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