The Tetrodotoxin-Resistant Na(+) Channel Nav1.8 is Essential for the Expression of Spontaneous Activity in Damaged Sensory Axons of Mice

The tetrodotoxin-resistant sodium channel α subunit, Nav1.8, is exclusively expressed in primary sensory neurons and is suggested to play a role in the generation of ectopic action potentials after axonal injury and thereby contribute to neuropathic pain. Here we investigated the involvement of Nav1...

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Autores principales: Roza, Carolina, Laird, Jennifer MA, Souslova, Veronika, Wood, John N, Cervero, Fernando
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2003
Materias:
Rapid Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343086/
https://ncbi.nlm.nih.gov/pubmed/12824446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.046110
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