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Glycosylation affects rat Kv1.1 potassium channel gating by a combined surface potential and cooperative subunit interaction mechanism

The effect of glycosylation on Kv1.1 potassium channel function was investigated in mammalian cells stably transfected with Kv1.1 or Kv1.1N207Q. Macroscopic current analysis showed that both channels were expressed but Kv1.1N207Q, which was not glycosylated, displayed functional differences compared...

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Detalhes bibliográficos
Main Authors: Watanabe, Itaru, Wang, Hong-Gang, Sutachan, Jhon J, Zhu, Jing, Recio-Pinto, Esperanza, Thornhill, William B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343013/
https://ncbi.nlm.nih.gov/pubmed/12879861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.040337
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