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Glia maturation factor overexpression in neuroblastoma cells activates glycogen synthase kinase-3β and caspase-3
In the present study we report that a replication-defective adenovirus construct of GMF cDNA (GMF-V) induced overexpression of GMF protein in neuroblastoma (N18) cells caused cytotoxicity and loss of cell viability. A significant increase in activation of GSK-3β occurred after infection with GMF-V w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2343001/ https://ncbi.nlm.nih.gov/pubmed/18054898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.11.011 |
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