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Glia maturation factor overexpression in neuroblastoma cells activates glycogen synthase kinase-3β and caspase-3

In the present study we report that a replication-defective adenovirus construct of GMF cDNA (GMF-V) induced overexpression of GMF protein in neuroblastoma (N18) cells caused cytotoxicity and loss of cell viability. A significant increase in activation of GSK-3β occurred after infection with GMF-V w...

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Detalhes bibliográficos
Main Authors: Zaheer, Asgar, Knight, Scott, Zaheer, Ashna, Ahrens, Marcus, Sahu, Shailendra K., Yang, Baoli
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343001/
https://ncbi.nlm.nih.gov/pubmed/18054898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.11.011
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