Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart

Opening of the mitochondrial permeability transition pore (MPTP) is thought to be a critical event in mediating the damage to hearts that accompanies their reperfusion following prolonged ischaemia. Protection from reperfusion injury occurs if the prolonged ischaemic period is preceded by short isch...

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Autors principals: Javadov, Sabzali A, Clarke, Samantha, Das, Manika, Griffiths, Elinor J, Lim, Kelvin H H, Halestrap, Andrew P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342939/
https://ncbi.nlm.nih.gov/pubmed/12692185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.034231
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