Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes

Mutations in the human SLC26A3 gene, also known as down-regulated in adenoma (hDRA), cause autosomal recessive congenital chloride-losing diarrhoea (CLD). hDRA expressed in Xenopus oocytes mediated bidirectional Cl(−)-Cl(−) and Cl(−)-HCO(3)(−) exchange. In contrast, transport of oxalate was low, and...

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Bibliografiske detaljer
Main Authors: Chernova, Marina N, Jiang, Lianwei, Shmukler, Boris E, Schweinfest, Clifford W, Blanco, Paola, Freedman, Steven D, Stewart, Andrew K, Alper, Seth L
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342915/
https://ncbi.nlm.nih.gov/pubmed/12651923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.039818
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