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Loss of the PTCH1 Gene Locus in Cardiac Fibroma
Cardiac fibroma is more commonly encountered in patients with Gorlin syndrome than the general population. Mutations of the tumor suppressor gene PTCH1 localized to 9q22.3 are the underlying cause of Gorlin syndrome. In this study, homozygous or heterozygous loss of the PTCH1 locus was identified in...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2342874/ https://ncbi.nlm.nih.gov/pubmed/18329553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2007.08.001 |
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