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Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing

Cyclic AMP-dependent protein kinase (PKA) targets contractile proteins, troponin-I (TnI) and myosin binding protein C (MyBP-C) in the heart and induces a decrease in myofilament Ca(2+) sensitivity. Yet, the effect of sarcomere length (SL) change on Ca(2+) sensitivity (length-dependent activation: LD...

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Bibliografiska uppgifter
Huvudupphovsmän: Konhilas, John P, Irving, Thomas C, Wolska, Beata M, Jweied, Eias E, Martin, Anne F, John Solaro, R, de Tombe, Pieter P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342721/
https://ncbi.nlm.nih.gov/pubmed/12562915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.038117
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