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Reduced contraction strength with increased intracellular [Ca(2+)] in left ventricular trabeculae from failing rat hearts

Intracellular calcium ([Ca(2+)](i)) and isometric force were measured in left ventricular (LV) trabeculae from spontaneously hypertensive rats (SHR) with failing hearts and normotensive Wistar-Kyoto (WKY) controls. At a physiological stimulation frequency (5 Hz), and at 37 °C, the peak stress of SHR...

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Sonraí Bibleagrafaíochta
Main Authors: Ward, Marie-Louise, Pope, Adèle J, Loiselle, Denis S, Cannell, Mark B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342526/
https://ncbi.nlm.nih.gov/pubmed/12527740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.029132
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