Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

Telomerase is a specialized reverse transcriptase consisting of both RNA and protein components. Previous characterization of yeast telomerase function in vivo identified four EST (for ever shorter telomeres) genes that, when mutated, result in the phenotypes expected for a defect in telomerase. Con...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lingner, Joachim, Cech, Thomas R., Hughes, Timothy R., Lundblad, Victoria
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11190
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