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An Essential Role for PICK1 in NMDA Receptor-Dependent Bidirectional Synaptic Plasticity
PICK1 is a calcium-sensing, PDZ domain-containing protein that interacts with GluR2 and GluR3 AMPA receptor (AMPAR) subunits and regulates their trafficking. Although PICK1 has been principally implicated in long-term depression (LTD), PICK1 over expression in CA1 pyramidal neurons causes a CaMK- an...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2336895/ https://ncbi.nlm.nih.gov/pubmed/18367088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.01.028 |
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