Lis1 Is Necessary for Normal Non-Radial Migration of Inhibitory Interneurons

Type I lissencephaly is a central nervous system (CNS) malformation characterized by mental retardation and epilepsy. These clinical features suggest a deficit in inhibitory neurons may, in part, underlie the pathogenesis of this disorder. Mutations in, or deletions of, LIS1 are the most commonly re...

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Detaylı Bibliyografya
Asıl Yazarlar: McManus, Matthew F., Nasrallah, Ilya M., Pancoast, MacLean M., Wynshaw-Boris, Anthony, Golden, Jeffrey A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2004
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2336110/
https://ncbi.nlm.nih.gov/pubmed/15331402
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