Lung Lining Fluid Glutathione Attenuates IL-13–Induced Asthma

GGT(enu1) mice, deficient in γ-glutamyl transferase and unable to metabolize extracellular glutathione, develop intracellular glutathione deficiency and oxidant stress. We used intratracheal IL-13 to induce airway inflammation and asthma in wild-type (WT) and GGT(enu1) mice to determine the effect o...

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Autors principals: Lowry, Matthew H., McAllister, Brian P., Jean, Jyh-Chang, Brown, Lou Ann S., Hughey, Rebecca P., Cruikshank, William W., Amar, Sal, Lucey, Edgar C., Braun, Kathleen, Johnson, Pamela, Wight, Thomas N., Joyce-Brady, Martin
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335334/
https://ncbi.nlm.nih.gov/pubmed/18063838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0128OC
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