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Efficient termination of transcription by RNA polymerase I requires the 5′ exonuclease Rat1 in yeast
During transcription termination by RNA polymerase II on protein-coding genes, the nuclear 5′ exonuclease Rat1/Xrn2 degrades the nascent transcript downstream from the polyadenylation site and “torpedoes” the polymerase. We report that the activity of Rat1 is also required for efficient termination...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335327/ https://ncbi.nlm.nih.gov/pubmed/18413717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.463708 |
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