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Significance analysis of microarray for relative quantitation of LC/MS data in proteomics

BACKGROUND: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positive and false negative rates that is often desirable in a large-scale quantitative proteomic analysis. We explore the possi...

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Detalhes bibliográficos
Main Authors: Roxas, Bryan AP, Li, Qingbo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335280/
https://ncbi.nlm.nih.gov/pubmed/18402702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-187
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