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A structural insight into lead neurotoxicity and calmodulin activation by heavy metals

Calmodulin is a calcium sensor that is also capable of binding and being activated by other metal ions. Of specific interest in this respect is lead, which is known to be neurotoxic and to have a very high affinity towards calmodulin. Crystal structures of human calmodulin complexed with lead and ba...

詳細記述

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書誌詳細
主要な著者: Kursula, Petri, Majava, Viivi
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335165/
https://ncbi.nlm.nih.gov/pubmed/17671360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107034525
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