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A structural insight into lead neurotoxicity and calmodulin activation by heavy metals
Calmodulin is a calcium sensor that is also capable of binding and being activated by other metal ions. Of specific interest in this respect is lead, which is known to be neurotoxic and to have a very high affinity towards calmodulin. Crystal structures of human calmodulin complexed with lead and ba...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335165/ https://ncbi.nlm.nih.gov/pubmed/17671360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107034525 |
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