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Binding assay and preliminary X-ray crystallographic analysis of ACTIBIND, a protein with anticarcinogenic and antiangiogenic activities

ACTIBIND is a T2 RNase extracellular glycoprotein produced by the mould Aspergillus niger B1 (CMI CC 324626) that possesses anticarcinogenic and antiangiogenic activities. ACTIBIND was found to be an actin-binding protein that interacts with rabbit muscle actin in a 1:2 molar ratio (ACTIBIND:actin)...

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Main Authors: de Leeuw, Marina, Roiz, Levava, Smirnoff, Patricia, Schwartz, Betty, Shoseyov, Oded, Almog, Orna
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335156/
https://ncbi.nlm.nih.gov/pubmed/17671376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107034483
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